Zack Ryder disagreed about what to call it, suggesting instead Team Co-Bro (formerly stylized by fan as Cobro/CoBro).
Both stars' preferred names names are portmanteaus. The first of their surnames, Marrella and Ryder. The second of their favourite themes, Cobras and Bro(ski)s.
In 2012, the name "Team Co-Bro" was affirmed by Michael Cole to be the name the pair chose to go with on the October 8 Raw. Prior to that, the group's former argument about what to call themselves had largely been forgotten and they had just been referred to as Santino Marella and Zack Ryder or vice versa.
Both having a background as heels, Santino was the first to turn face, and actually faced Zack as an opponent in 2010. On the July 19 Raw, Santino paired with Vladimir Kozlov to defeat Ryder & William Regal. Kozlov was generally Santino's partner for a long while until leaving in 2011.
Santino and Zack actually began teaming together prior to Santino losing the championship.
He then began teaming with Zack Ryder, beginning on the July 21, 2011 episode of WWE Superstars Santino teamed with Ryder in a winning effort against the WWE tag team champions David Otunga and Michael McGillicutty.
On the Aug 1, 2011 Raw they once again faced Otunga and McGillicutty but lost.
During the 2012 WWE Tag Team Championship Tournament, Team Co-Bro faced off against Justin Gabriel & Tyson Kidd during WWE Main Event on October 3, 2012. Team Co-Bro won by pinfall, and went on to face Team Rhodes Scholars (Cody Rhodes & Damien Sandow) in the semi-finals. On the October 8 edition of RAW, The Rhodes Scholars defeated Team Co-Bro by pinfall.