The October 15, 2021 Edition of Smackdown Live was a Professional wrestling television show of the WWE's Smackdown brand which took place on October 15, 2021 at the Toyota Arena in Ontario, California.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Dark Match: Keith Lee defeated Gino Rivera
- Dark Match: Xia Li defeated Aliyah
- Finn Bálor defeated Sami Zayn in a King of the Ring tournament Semi Final Match (11:25)
- Sonya Deville & Shayna Baszler defeated Naomi in a Two on One Handicap Match (2:00)
- Zelina Vega defeated Carmella in a Queen's Crown tournament Semi Final Match (2:40)
- The Usos (Jimmy Uso & Jey Uso) (c) defeated The Street Profits (Angelo Dawkins & Montez Ford) in a Street Fight to retain the WWE Smackdown Tag Team Championship (11:00)
- Sasha Banks defeated Becky Lynch (17:45)
Other on-screen talent
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- WWE Smackdown Live #1156 at CAGEMATCH.net
- WWE Smackdown Live #1156 at WWE.com
- [ Smackdown #1156 on WWE Network]