NJPW Road To Destruction 2019 - Night 5 was a professional wrestling event promoted by New Japan Pro-Wrestling (NJPW) that took place on September 10, 2019 in Fuji, Shizuoka at the Fujisan Messe.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Karl Fredericks  defeated Yuya Uemura  (6:12) in a 12th Young Lions Cup League Match
- Shota Umino  defeated Michael Richards  (8:00) in a 12th Young Lions Cup League Match
- Alex Coughlin, Clark Connors & Satoshi Kojima defeated Hiroyoshi Tenzan, Ren Narita & Yota Tsuji (11:11)
- CHAOS (Tomohiro Ishii & YOSHI-HASHI), Ryusuke Taguchi, Toa Henare & Togi Makabe defeated BULLET CLUB (Bad Luck Fale, Jado, Tama Tonga, Tanga Loa & Yujiro Takahashi) (13:13)
- BULLET CLUB (Chase Owens, El Phantasmo & Taiji Ishimori) defeated Birds Of Prey (Robbie Eagles & Will Ospreay) & Tomoaki Honma (10:05)
- Roppongi 3K (SHO & YOH), Hiroshi Tanahashi & Jushin Thunder Liger defeated Suzuki-gun (DOUKI, Minoru Suzuki, Yoshinobu Kanemaru & Zack Sabre Jr.) (11:14)
- Los Ingobernables de Japon (EVIL, SANADA & Shingo Takagi) defeated CHAOS (Hirooki Goto, Kazuchika Okada & Rocky Romero) (13:06)
- Los Ingobernables de Japon (BUSHI & Tetsuya Naito) defeated BULLET CLUB (Gedo & Jay White) (12:52)