NJPW Road To Destruction 2019 - Night 10 was a professional wrestling event promoted by New Japan Pro-Wrestling (NJPW) that took place on September 19, 2019 in Tottori, Japan at the Tottori Industrial Gymnasium.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Shota Umino  defeated Yota Tsuji  (7:34) in a 12th Young Lions Cup League Match
- Karl Fredericks  defeated Michael Richards  (6:12) in a 12th Young Lions Cup League Match
- Ren Narita, Yuji Nagata & Yuya Uemura defeated Alex Coughlin, Clark Connors & Manabu Nakanishi (8:50)
- BULLET CLUB (Bad Luck Fale, Chase Owens, Tama Tonga & Tanga Loa) defeated CHAOS (Tomohiro Ishii & YOSHI-HASHI), Tiger Mask & Toa Henare (9:52)
- BULLET CLUB (El Phantasmo, KENTA, Taiji Ishimori & Yujiro Takahashi) defeated Birds Of Prey (Robbie Eagles & Will Ospreay), Kota Ibushi & Tomoaki Honma (10:50)
- Roppongi 3K (SHO & YOH), Hiroshi Tanahashi & Togi Makabe defeated Suzuki-gun (DOUKI, Minoru Suzuki, Yoshinobu Kanemaru & Zack Sabre Jr.) (11:04)
- CHAOS (Hirooki Goto, Kazuchika Okada & Rocky Romero) defeated Los Ingobernables de Japon (BUSHI, SANADA & Shingo Takagi) (10:51)
- Los Ingobernables de Japon (EVIL & Tetsuya Naito) defeated BULLET CLUB (Gedo & Jay White) (15:05)
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