The January 25, 2008 Edition of Smackdown is a Professional wrestling television show of the WWE's Smackdown brand, it was taped on January 22, 2008 at the John Paul Jones Arena in Charlottesville, Virginia. This was the first episode of Smackdown to broadcast in High Definition.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Dark Match: Paul Burchill (w/ Katie Lea) defeated Funaki
- Rey Mysterio defeated Curt Hawkins & Zack Ryder by DQ in a Two On One Handicap Match (5:34)
- Jimmy Wang Yang (w/ Shannon Moore) defeated Domino (w/ Cherry & Deuce) (5:26)
- Chuck Palumbo, Jamie Noble & Michelle McCool vs. John Morrison, Layla & The Miz ended in a no contest
- Finlay (w/ Hornswoggle) vs. The Great Khali (w/ Ranjin Singh) in a Belfast Brawl Match ended in a no contest
- The Undertaker defeated Big Daddy V (w/ Matt Striker) (6:11)
- Edge (w/ Curt Hawkins & Zack Ryder) defeated CM Punk (10:07)
- Dark Match: Batista, CM Punk & Rey Mysterio defeated Curt Hawkins, Edge & Zack Ryder