The December 10, 2021 Edition of Smackdown Live is a Professional wrestling television show of the WWE's Smackdown brand, which took place on December 10, 2021 at the Staples Center in Los Angeles, California.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Shinsuke Nakamura & Rick Boogs defeated Los Lotharios (Angel & Humberto) (1:22)
- Drew McIntyre defeated Sheamus (7:22)
- Toni Storm defeated Charlotte Flair by DQ (3:17)
- The New Day (King Woods & Sir Kingston) defeated The Usos (Jimmy Uso & Jey Uso) and RK-Bro (Randy Orton & Riddle) (18:56)
- Dark Match: Sasha Banks defeated Becky Lynch, Bianca Belair and Charlotte Flair in a Fatal Four Way Match
Other on-screen talent
- WWE Smackdown Live #1164 at CAGEMATCH.net
- WWE Smackdown Live #1164 at WWE.com
- Smackdown #1164 on WWE Network